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At a glance
Originator
Bristol-Myers Squibb
Developer
Retrophin
Class
Antihypertensives; Isoxazoles; Nerve growth factors; Small molecules; Spiro compounds; Sulfonamides; Urologics
Mechanism of Action
Angiotensin type 1 receptor antagonists; Endothelin A receptor antagonists
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Yes
-
Focal segmental glomerulosclerosis
New Molecular Entity
Yes
Highest Development Phases
Phase III
Focal segmental glomerulosclerosis; IgA nephropathy
Discontinued
Hypertension
Most Recent Events
10 Mar 2020
Ligand Pharmaceuticals anticipates launch of sparsentan by the end of 2022
09 Mar 2020
Retrophin announces intention to submit Conditional Marketing Authorization (CMA) for Focal segmental glomerulosclerosis in EU
24 Feb 2020
Retrophin announces intention to submit NDA to the US FDA for Focal segmental glomerulosclerosis
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