Research programme: topoisomerase II inhibitors - Reata Pharmaceuticals

Drug Profile

Research programme: topoisomerase II inhibitors - Reata Pharmaceuticals

Alternative Names: Doxorubicin analogues - Reata; Reata 769; RTA 769; WP769

Latest Information Update: 12 Oct 2015

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At a glance

  • Originator University of Texas M. D. Anderson Cancer Center
  • Developer Reata Pharmaceuticals
  • Class
  • Mechanism of Action Apoptosis stimulants; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Brain cancer; Cancer

Most Recent Events

  • 09 May 2007 Preclinical data presented at the 98th Annual Meeting of the American Association for Cancer Research (AACR-2007) added to the pharmacokinetics section
  • 19 Apr 2006 This programme is still in active development
  • 31 Oct 2004 Preclinical trials in Brain cancer in USA (PO)
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