Yttrium 90-radiolabelled OTSA 101

Drug Profile

Yttrium 90-radiolabelled OTSA 101

Alternative Names: Frizzled homologue 10 antibodies - OncoTherapy Science; Frizzled-10 antibodies - OncoTherapy Science; Fz-10 antibodies - OncoTherapy Science; FZD10 monoclonal antibodies - OncoTherapy Science; hFz10 antibodies - OncoTherapy Science; OTSA 101 DTPA-90Y; OTSA101; TT641 pAb - OncoTherapy Science

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator OncoTherapy Science
  • Developer Centre Leon Berard; OncoTherapy Science
  • Class Antineoplastics; Monoclonal antibodies; Radiopharmaceuticals; Radiosensitisers
  • Mechanism of Action Wnt signalling pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Synovial sarcoma
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Synovial sarcoma

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Synovial-sarcoma in France (Parenteral)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Synovial-sarcoma in Japan (Parenteral)
  • 02 Jun 2017 Efficacy and adverse events data from a phase I trial in Synovial sarcoma presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
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