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Fremanezumab - Teva Pharmaceutical Industries

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Drug Profile

Fremanezumab - Teva Pharmaceutical Industries

Alternative Names: AJOVY; Anti-calcitonin gene-related peptide monoclonal antibody; Anti-CGRP monoclonal antibody; fremanezumab-vfrm; LBR-101; PF-04427429; PF-4427429; RN-307; TEV-48125

Latest Information Update: 18 Apr 2025

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At a glance

  • Originator Rinat Neuroscience
  • Developer Otsuka Pharmaceutical; Rinat Neuroscience; Teva Pharmaceutical Industries
  • Class Analgesics; Antimigraines; Monoclonal antibodies
  • Mechanism of Action Calcitonin gene-related peptide antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Migraine
  • Phase II Fibromyalgia; Headache; Interstitial cystitis
  • Discontinued Cluster headache

Most Recent Events

  • 07 Apr 2025 Preregistration for Migraine (Prevention, In adolescents, In children) in USA (SC)
  • 07 Apr 2025 US FDA accepts sBLA for fremanezumab for Migraine in children and adolescent patients aged 6-17 years for review
  • 04 Dec 2024 Efficacy and adverse events data from a phase III SPACE trial in Migraine released by Teva Pharmaceuticals

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