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Research programme: proteolytic bacterial enzymes - Hansa Biopharam AB

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Drug Profile

Research programme: proteolytic bacterial enzymes - Hansa Biopharam AB

Alternative Names: Endoglycosidase of Streptococcus pyogenes; EndoS; NiceR; Second generation IdeS; Second generation Ig-G-degrading enzyme of Streptococcus pyogenes

Latest Information Update: 27 Dec 2022

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At a glance

  • Originator Hansa Medical AB
  • Developer Hansa Biopharma AB
  • Class Anti-inflammatories; Antibacterials; Antineoplastics; Antirheumatics; Bacterial proteins; Enzymes; Immunotherapies
  • Mechanism of Action Immunoglobulin modulators; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Cancer; Transplant rejection
  • Discontinued Rheumatoid arthritis; Streptococcal infections

Most Recent Events

  • 27 Dec 2022 Preclinical development is ongoing in Cancer, Transplant rejection and Autoimmune disorders in Sweden (Parenteral)
  • 21 Oct 2020 Hansa Biopharma plans IND-enabling toxicity studies in first half of 2021
  • 28 May 2020 No recent reports of development identified for preclinical development in Autoimmune-disorders in Sweden (Parenteral)

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