AAV2sFLT 01 - Applied Genetic Technologies/Sanofi Genzyme

Drug Profile

AAV2sFLT 01 - Applied Genetic Technologies/Sanofi Genzyme

Alternative Names: AAV2-sFLT01; age-related macular degeneration gene therapy - Applied Genetic Technologies/Sanofi Genzyme; anti vascular endothelial growth factor (VEGF) gene therapy - Applied Genetic Technologies/Sanofi Genzyme; GZ-402663; sFLT-01

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Applied Genetic Technologies Corporation; Genzyme Corporation
  • Developer Applied Genetic Technologies Corporation; Genzyme Corporation; JDRF
  • Class Eye disorder therapies; Gene therapies
  • Mechanism of Action Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Age-related macular degeneration; Diabetic retinopathy

Most Recent Events

  • 16 Jul 2013 Genzyme enters cross-license agreement for use of Asklepios BioPharmaceutical's Duplex gene therapy vector technology for Genzyme's internal product development research (including AAV2sFLT-01 for age-related macular degeneration) and external sublicensing
  • 25 Oct 2012 Phase-I development is ongoing in USA
  • 08 Apr 2011 Genzyme Corporation has been acquired by sanofi-aventis
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