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Resveratrol - Sirtris

Drug Profile

Resveratrol - Sirtris

Alternative Names: 184072; GSK184072; SRT 501

Latest Information Update: 31 Dec 2021

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At a glance

  • Originator Sirtris Pharmaceuticals
  • Developer GlaxoSmithKline; Sirtris
  • Class Antidementias; Antineoplastics; Antithrombotics; Cardiovascular therapies; Neuroprotectants; Nonsteroidal anti-inflammatories; Phenols; Small molecules; Stilbenes; Vasodilators
  • Mechanism of Action Antioxidants; Ribonucleotide reductase inhibitors; SIRT1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - MELAS syndrome

Highest Development Phases

  • Discontinued Cancer metastases; Colorectal cancer; MELAS syndrome; Multiple myeloma; Multiple sclerosis; Optic neuritis; Type 2 diabetes mellitus

Most Recent Events

  • 02 Dec 2010 Discontinued - Phase-II for Multiple myeloma in Denmark (PO)
  • 02 Dec 2010 Discontinued - Phase-II for Multiple myeloma in United Kingdom (PO)
  • 22 Apr 2010 Suspended - Phase-II for Multiple myeloma in combination with bortezomib in Denmark (PO)
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