Bupropion/zonisamide
Alternative Names: Bupropion SR/zonisamide IR; Bupropion SR/zonisamide SR; Empatic™; Excalia™; Zonisamide IR/bupropion SR; Zonisamide SR/bupropion SR; Zonisamide/bupropionLatest Information Update: 01 Sep 2015
At a glance
- Originator Orexigen Therapeutics
- Class Antidepressants; Antiepileptic drugs; Isoxazoles; Obesity therapies; Propiophenones; Sulfonamides
- Mechanism of Action Adrenergic uptake inhibitors; Antioxidants; Calcium channel antagonists; Dopamine release stimulants; Dopamine uptake inhibitors; Neuron inhibitors; Serotonin release stimulants; Sodium channel antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
- Available For Licensing Yes
Highest Development Phases
- Discontinued Obesity
Most Recent Events
- 20 Mar 2013 Bupropion/Zonisamide is available for licensing as of 20 Mar 2013. www.orexigen.com
- 30 Sep 2009 Efficacy and adverse events data from a phase IIb trial in obesity released by Orexigen Therapeutics
- 09 Oct 2008 Data from two post-hoc analyses from a phase IIb trial in Obesity presented at the 2008 Obesity Society Annual Scientific Meeting