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Serlopitant - Menlo Therapeutics

Drug Profile

Serlopitant - Menlo Therapeutics

Alternative Names: JTS 661; MK-0594; VPD-737

Latest Information Update: 07 Nov 2019

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At a glance

  • Originator Merck & Co
  • Developer Epidermolysis Bullosa Research Partnership; Japan Tobacco; Menlo Therapeutics; Merck & Co; Stanford University; Torii Pharmaceutical
  • Class Antipruritics; Antitussives; Cyclopentanes; Isoindoles; Skin disorder therapies; Small molecules; Urologics
  • Mechanism of Action Neurokinin 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Pruritus
  • Discontinued Alcoholism; Cough; Overactive bladder

Most Recent Events

  • 31 Oct 2019 Menlo Therapeutics plans a phase-III trial for Pruritus (associated with Psoriasis) in 2020
  • 29 Oct 2019 Menlo Therapeutics intends to file NDA for Pruritus (associated with Prurigo nodularis) in second half of 2020
  • 29 Oct 2019 Menlo Therapeutics completes enrolment in its phase III trial for Pruritus (associated with Prurigo nodularis) in Austria, Poland and Germany
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