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Serlopitant - VYNE Therapeutics

Drug Profile

Serlopitant - VYNE Therapeutics

Alternative Names: JTS 661; MK-0594; VPD-737

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Merck & Co
  • Developer Japan Tobacco; Menlo Therapeutics; Merck & Co; Torii Pharmaceutical
  • Class Antipruritics; Antitussives; Cyclopentanes; Isoindoles; Skin disorder therapies; Small molecules; Urologics
  • Mechanism of Action Neurokinin 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alcoholism; Cough; Overactive bladder; Pruritus

Most Recent Events

  • 24 Jun 2022 Stanford University, Epidermolysis Bullosa Research Partnership and Menlo Therapeutics completes a phase II trial in Pruritus (In adolescents, In adults, In the elderly) in USA (PO, Tablet) (NCT03836001)
  • 08 Sep 2020 Menlo Therapeutics is now called VYNE Therapeutics
  • 17 Jun 2020 Menlo Therapeutics terminates a phase III trial in Pruritus (associated with prurigo nodularis, atopic dermatitis, or psoriasis) in USA, Austria, Germany, Poland (PO) (NCT03540160)
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