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Basimglurant - Noema Pharma

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Drug Profile

Basimglurant - Noema Pharma

Alternative Names: NOE-101; RG-7090; RO-4917523

Latest Information Update: 21 Aug 2024

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At a glance

  • Originator Roche
  • Developer Chugai Pharmaceutical; Noema Pharma; Roche
  • Class Analgesics; Antidepressants; Antiepileptic drugs; Fluorobenzenes; Halogenated hydrocarbons; Imidazoles; Pyridines; Small molecules
  • Mechanism of Action Metabotropic glutamate receptor 5 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Fragile X syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Trigeminal neuralgia
  • Phase II Tuberous sclerosis
  • Preclinical Idiopathic pulmonary fibrosis
  • Discontinued Fragile X syndrome; Major depressive disorder

Most Recent Events

  • 13 Aug 2024 Noema Pharma completes enrolment in its phase-II GALENE clinical trials in Tuberous sclerosis (Adjunctive treatment, In children, In adolescents) in United Kingdom, Turkey, Spain, Poland, Italy, Israel, India (Parenteral)
  • 24 Jun 2024 Preclinical trials in Idiopathic pulmonary fibrosis in Switzerland (unspecified route)
  • 17 May 2024 Pharmacodynamics data from a preclinical study in Idiopathic pulmonary fibrosis at 120th International Conference of the American Thoracic Society (ATC-2024)

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