Drug Profile


Alternative Names: Clot-buster protein; Clot-specific streptokinase; CSSK; SMRX11

Latest Information Update: 01 Aug 2018

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At a glance

  • Originator Institute of Microbial Technology
  • Developer Nostrum Pharmaceuticals; Symmetrix Biotech
  • Class Coenzymes; Plasminogen activator enzymes; Recombinant fusion proteins; Recombinant proteins; Thrombolytics
  • Mechanism of Action Fibrinolytic agents; Plasmin stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Myocardial infarction
  • No development reported Thrombosis

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Thrombosis(In volunteers) in India (IV)
  • 24 Mar 2014 SMRX 11 is still in preclinical trials for thrombosis (IV) in India
  • 10 Mar 2014 Symmetrix Pharmaceuticals plans a phase II trial for Myocardial infarction in India (CTRI/2014/03/004442)
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