Drug Profile
OBI 3424
Alternative Names: AST-3424; OBI-3424; TH-3424Latest Information Update: 18 Dec 2023
Price :
$50
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At a glance
- Originator Threshold Pharmaceuticals
- Developer Ascentawits Pharmaceuticals; National Cancer Institute (USA); OBI Pharma
- Class Antineoplastics; Small molecules
- Mechanism of Action Alkylating agents; DNA cross linking agents
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Precursor T-cell lymphoblastic leukaemia-lymphoma
- Phase I/II Liver cancer; Pancreatic cancer; Prostate cancer; Solid tumours
Most Recent Events
- 20 Oct 2023 Pharmacodynamics data from a preclinical trial in Cancer presented at the European Society for Medical Oncology Congress (ESMO-2023)
- 03 Jun 2022 Safety and pharmacokinetic data from a phase I part of phase I/II trial in Solid tumours presented at 58th Annual Meeting of the American Society of Clinical Oncology (ASCO-2022)
- 08 Apr 2022 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 113th Annual Meeting of the American Association for Cancer Research (AACR-2022)