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NTX 010

Drug Profile

NTX 010

Alternative Names: NTX-010; Seneca Valley Virus-001; SVV-001

Latest Information Update: 18 May 2017

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At a glance

  • Originator Novartis
  • Developer Alliance for Clinical Trials in Oncology; National Cancer Institute (USA); Neotropix; North Central Cancer Treatment Group
  • Class Antineoplastics; Oncolytic viruses
  • Mechanism of Action Apoptosis stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • No development reported Neuroendocrine tumours; Small cell lung cancer

Most Recent Events

  • 28 Mar 2017 NCI terminates a phase II trial as interim analysis declared futility in Small cell lung cancer (Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT01017601)
  • 31 May 2013 Safety and efficacy data from a phase II trial in Small cell lung cancer presented at the 49th Annual Meeting of the American Society of Clinical Oncology
  • 23 Feb 2010 Neotropix completes enrolment in its Phase-I trial (NCT00314925) for Neuroendocrine tumours in USA
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