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Research programme: DNA interference therapies - Sierra Oncology

Drug Profile

Research programme: DNA interference therapies - Sierra Oncology

Alternative Names: PNT 100; PNT 200; PNT 300; PNT 400; PNT 500; PNT 600

Latest Information Update: 17 Apr 2019

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At a glance

  • Originator ProNAi Therapeutics
  • Developer Sierra Oncology
  • Class Oligonucleotides
  • Mechanism of Action BIRC5 protein modulators; DNA modulators; KRAS protein modulators; Proto-oncogene protein c-bcl-2 modulators; STAT3 transcription factor modulators; Transforming growth factor alpha modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Cancer in USA
  • 09 Jan 2017 ProNAi Therapeutics is now called Sierra Oncology
  • 03 Nov 2015 Marina Biotech has patent protection for SMARTICLES® delivery technology and for the composition of NOV 340 in Canada
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