R 763
Alternative Names: AS703569; R763Latest Information Update: 01 Apr 2011
At a glance
- Originator Rigel Pharmaceuticals
- Developer Merck Serono
- Class Antineoplastics; Small molecules
- Mechanism of Action Aurora kinase A inhibitors; Aurora kinase B inhibitors; Aurora kinase C inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Highest Development Phases
- Discontinued Haematological malignancies; Solid tumours
Most Recent Events
- 28 Feb 2010 Merck Serono expects to wind down the various clinical trials for R 763 and plans to return the drug back to Rigel
- 19 Nov 2009 Efficacy, adverse events & pharmacokinetic data from a phase I trial in Solid tumours presented at the 21st AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2009)
- 19 Nov 2009 Preclinical pharmacodynamics data in Haematological malignancies presented at the 21st AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2009)