Mogamulizumab - Kyowa Hakko Kirin

Drug Profile

Mogamulizumab - Kyowa Hakko Kirin

Alternative Names: AMG-761; KW-0761; Mogamulizumab-kpkc; Poteligeo

Latest Information Update: 06 Nov 2018

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At a glance

  • Originator Kyowa Hakko
  • Developer Amgen; Bristol-Myers Squibb; Kyowa Hakko Kirin; Ono Pharmaceutical
  • Class Antiasthmatics; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action CCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T cell lymphoma; Peripheral T-cell lymphoma; Adult T-cell leukaemia-lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Adult T-cell leukaemia-lymphoma; Cutaneous T cell lymphoma; Peripheral T-cell lymphoma
  • Phase III Spinal cord disorders
  • Phase I/II Solid tumours
  • Research Mycosis fungoides; Sezary syndrome
  • No development reported Non-small cell lung cancer
  • Discontinued Asthma; Hypersensitivity

Most Recent Events

  • 30 Sep 2018 Discontinued - Phase-I for Solid tumours in Japan (IV) (Kyowa pipeline, November 2018)
  • 28 Sep 2018 Efficacy data from the phase III MAVORIC trial in Cutaneous T-cell lymphoma (CTCL) released by Kyowa Kirin
  • 21 Sep 2018 Kyowa Hakko Kirin expects European Commissions (EC) final decision on the grant of marketing authorisation by end of 2018
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