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Elafibranor - Ipsen

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Drug Profile

Elafibranor - Ipsen

Alternative Names: GFT-505; IPN-60190; IQIRVO; Iqirvo

Latest Information Update: 18 Dec 2024

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At a glance

  • Originator Genfit
  • Developer Genfit; Ipsen
  • Class Anti-inflammatories; Antifibrotics; Antihyperglycaemics; Antihyperlipidaemics; Hepatoprotectants; Organic sulfur compounds; Phenyl ethers; Propionic acids; Small molecules
  • Mechanism of Action Peroxisome proliferator-activated receptor alpha agonists; Peroxisome proliferator-activated receptor delta agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Primary biliary cirrhosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Primary biliary cirrhosis
  • Phase III Primary sclerosing cholangitis
  • Discontinued Hepatic fibrosis; Lipid metabolism disorders; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Type 2 diabetes mellitus

Most Recent Events

  • 09 Dec 2024 Ipsen plans a phase III trial for Primary biliary cholangitis (Treatment-experienced) (PO, Tablet) (NCT06730061)
  • 15 Nov 2024 Updated efficacy and adverse event data from a phase III trial in Primary biliary cirrhosis released by Ipsen
  • 22 Oct 2024 NICE approved elafibranor for the treatment of primary biliary cirrhosis

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