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Funapide - Xenon Pharmaceuticals

Drug Profile

Funapide - Xenon Pharmaceuticals

Alternative Names: TV-45070; XEN 402; XPF 001; XPF-002

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Xenon Pharmaceuticals
  • Developer Teva Pharmaceutical Industries; Xenon Pharmaceuticals
  • Class Benzodioxoles; Fluorobenzenes; Furans; Indoles; Non-opioid analgesics; Small molecules; Spiro compounds
  • Mechanism of Action Nav1.7 voltage-gated sodium channel inhibitors; Nav1.8 voltage-gated sodium channel inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Erythromelalgia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Neuropathic pain; Postherpetic neuralgia
  • Discontinued Dental pain; Erythromelalgia; Musculoskeletal pain; Pain

Most Recent Events

  • 28 Mar 2018 Xenon Pharmaceutical and Teva terminate its licence agreement for Funapide
  • 24 Oct 2017 Discontinued - Phase-II for Erythromelalgia in USA (Topical) (Xenon pipeline and Teva Pharmaceutical Industries pipeline, October 2017)
  • 24 Oct 2017 Phase-II clinical trials in Neuropathic pain before October 2017 (Topical) (Teva Pharmaceutical Industries pipeline, October 2017)
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