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Amatuximab - Eisai

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Drug Profile

Amatuximab - Eisai

Alternative Names: Anti-mesothelin monoclonal antibody; MORAb-009; MORAB-009-006

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator National Cancer Institute (USA)
  • Developer Eisai Co Ltd; Eisai Inc
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Malignant-mesothelioma; Pancreatic cancer; Solid tumours

Most Recent Events

  • 29 Nov 2022 Discontinued - Phase-II for Malignant mesothelioma (Combination therapy, Inoperable/Unresectable, Late-stage disease) in Italy, United Kingdom, Germany, France, Australia, USA (IV)
  • 29 Nov 2022 Discontinued - Phase-II for Malignant mesothelioma in USA, Germany, Canada, Netherlands, Spain (IV)
  • 16 Apr 2021 Amatuximab is still in phase II trials for Malignant mesothelioma in Australia, Canada, France, Germany, Italy, Netherlands, Spain, USA, United Kingdom (Eisai pipeline, April 2021)
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