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Research programme: endopeptidase inhibitors - American Life Science Pharmaceuticals

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Drug Profile

Research programme: endopeptidase inhibitors - American Life Science Pharmaceuticals

Alternative Names: acetyl-L-leucyl-L-valyl-L-lysinal-aldehyde; ALP 496; ALSP Next generation compounds; CA 074Me; E 64d

Latest Information Update: 22 Feb 2023

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At a glance

  • Originator American Life Science Pharmaceuticals; Columbia University; University of Illinois at Chicago
  • Class Neuropeptides; Small molecules
  • Mechanism of Action Amyloid precursor protein secretase modulators; Cathepsin B inhibitors; Endopeptidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alzheimer's disease; Traumatic brain injuries

Most Recent Events

  • 22 Feb 2023 Preclinical development in Alzheimer's-disease is ongoing in USA (American Life Science Pharmaceuticals website, February 2023)
  • 22 Feb 2023 Preclinical development in Traumatic brain injuries is ongoing in USA (American Life Science Pharmaceuticals website, February 2023)
  • 28 Mar 2019 No recent reports of development identified for preclinical development in Traumatic brain injuries in USA

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