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Crenezumab - AC Immune/Genentech/Universidad-de-Antioquia

Drug Profile

Crenezumab - AC Immune/Genentech/Universidad-de-Antioquia

Alternative Names: Anti-Abeta antibody; MABT5102A; R 5490245; RG 7412; RO 5490245

Latest Information Update: 29 Aug 2019

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At a glance

  • Originator AC Immune; Universidad de Antioquia
  • Developer AC Immune; Genentech; Universidad de Antioquia
  • Class Antibodies; Antidementias; Monoclonal antibodies
  • Mechanism of Action Amyloid beta-protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Alzheimer's disease

Most Recent Events

  • 09 Aug 2019 Roche completes the phase III CREAD OLE trial in Alzheimer's disease in Australia, Canada, Finland, France, Germany, Hong Kong, Italy, South Korea, Lithuania, Mexico, Poland, Russia, Spain, Turkey, Ukraine, United Kingdom and USA (NCT03491150) (EudraCT2017-002702-12)
  • 30 Jun 2019 Genentech initiates a phase II trial for Alzheimer's disease in USA (IV) (SC) (NCT03977584)
  • 06 Jun 2019 Genentech plans a phase II trial for Alzheimer's disease in June 2019 (NCT03977584)
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