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Class
Antineoplastics; Immunotherapies; Monoclonal antibodies
Mechanism of Action
Antibody-dependent cell cytotoxicity; CD319 antigen modulators; Immunostimulants
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Yes
-
Multiple myeloma
New Molecular Entity
Yes
Highest Development Phases
Marketed
Multiple myeloma
Most Recent Events
23 Aug 2021
Bristol-Myers Squibb in a collaboration with Big Ten Cancer Research Consortium withdraw a phase II Immuno-POWER trial in Multiple myeloma (Combination therapy, Second-line therapy or greater, Maintenance therapy) before enrolment due to pulled funding support from funder (NCT04584307)
30 Jun 2021
University of Chicago, Bristol-Myers Squibb and Amgen suspends a phase II trial for Multiple myeloma (Combination therapy, First-line therapy, Newly diagnosed) in USA (IV) (NCT02969837)
04 Jun 2021
Interim efficacy and adverse event data from a phase II trial in Multiple myeloma presented at the 57th Annual Meeting of the American Society of Clinical Oncology (ASCO-2021)
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