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Cannabidiol - GW Pharmaceuticals

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Drug Profile

Cannabidiol - GW Pharmaceuticals

Alternative Names: CBD - GW Pharmaceuticals; CBD-OS - GW Pharmaceuticals; Epidiolex; Epidiolex/Epidyolex; EPIDIOLEXA; Epidyolex; GW-42003; GWP-42003; GWP-42003-P; JZP-926

Latest Information Update: 18 Dec 2025

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At a glance

  • Originator GW Pharmaceuticals
  • Developer GW Pharmaceuticals; Jazz Pharmaceuticals Inc; University of Alabama at Birmingham; University of Utah
  • Class Analgesics; Anti-inflammatories; Anti-ischaemics; Antiacnes; Antibacterials; Antiepileptic drugs; Antihyperglycaemics; Antihyperlipidaemics; Antineoplastics; Antiparkinsonians; Antipsoriatics; Antipsychotics; Antirheumatics; Anxiolytics; Behavioural disorder therapies; Cannabinoids; Cardiovascular therapies; Cyclohexenes; Drug withdrawal therapies; Heart failure therapies; Hepatoprotectants; Muscle relaxants; Neuroprotectants; Obesity therapies; Resorcinols; Skin disorder therapies; Small molecules
  • Mechanism of Action 5-HT1 serotonin receptor modulators; Antioxidants; Cannabinoid receptor CB1 inverse agonists; Cannabinoid receptor CB2 inverse agonists; Transient receptor potential channel modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Lennox-Gastaut syndrome; Dravet syndrome; Cerebral ischaemia; Infantile spasms; Tuberous sclerosis; Myoclonic epilepsies
  • New Molecular Entity No

Highest Development Phases

  • Marketed Dravet syndrome; Lennox-Gastaut syndrome; Tuberous sclerosis
  • Phase III Epilepsy; Infantile spasms; Rett syndrome
  • Phase II/III Blepharospasm
  • Phase II Autism spectrum disorder; Heroin-related disorders; Opioid-related disorders; Parkinson's disease; Sturge-Weber syndrome
  • Phase I Partial epilepsies
  • No development reported Cerebral ischaemia; Duchenne muscular dystrophy; Ovarian cancer
  • Discontinued Dyslipidaemias; Myoclonic epilepsies; Non-alcoholic fatty liver disease; Schizophrenia; Type 2 diabetes mellitus; Ulcerative colitis

Most Recent Events

  • 26 Nov 2025 Phase-I clinical trials in Partial epilepsies (In adults, In adolescents, In the elderly, Treatment-experienced) in USA (PO) (NCT07233239)
  • 18 Nov 2025 Jazz Pharmaceuticals plans a phase Ib trial for Partial epilepsies (In adolescents, In adults, In the elderly, Treatment-experienced) (PO, Solution) (NCT07233239)
  • 17 Jan 2025 GW Research terminates a phase-III trial in Epilepsy (Adjunctive treatment, In infants, Treatment-resistant) in the US, Italy and Spain (PO), due to business strategy (NCT04485104),

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