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Drug Profile

Mometasone/nortriptyline

Alternative Names: CRx-191; Nortriptyline/mometasone

Latest Information Update: 29 Mar 2011

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At a glance

Originator CombinatoRx
Developer Zalicus
Class Anti-inflammatories; Dibenzocycloheptenes; Glucocorticoids; Pregnadienediols
Mechanism of Action Lipocortin synthesis agonists; Phospholipase A2 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No

Highest Development Phases

Discontinued Psoriasis

Most Recent Events

31 Dec 2010 Discontinued - Phase-II for Psoriasis in Germany (Topical)
09 Sep 2010 CombinatoRx is now called Zalicus
13 Mar 2008 Interim efficacy and adverse event data from a phase II trial in psorasis released by CombinatoRx

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