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Bleselumab - Astellas Pharma/Kyowa Kirin

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Drug Profile

Bleselumab - Astellas Pharma/Kyowa Kirin

Alternative Names: 4D11; ASKP 1240

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Kirin Brewery
  • Developer Astellas Pharma; Kyowa Hakko Kirin; Kyowa Kirin
  • Class Antipsoriatics; Monoclonal antibodies
  • Mechanism of Action CD40 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Focal segmental glomerulosclerosis; Plaque psoriasis; Renal transplant rejection; Transplant rejection

Most Recent Events

  • 06 Aug 2021 Discontinued - Phase-I for Transplant rejection (In volunteers) in USA (SC) (Kyowa Kirin pipeline, August 2021)
  • 06 Aug 2021 Discontinued - Phase-I for Transplant rejection (Prevention) in Japan (IV) (Kyowa Kirin pipeline, August 2021)
  • 06 Aug 2021 Discontinued - Phase-II for Focal segmental glomerulosclerosis (Prevention) in USA, Canada (IV) (Kyowa Kirin pipeline, August 2021)

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