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Iobenguane I-123 - GE Healthcare

Drug Profile

Iobenguane I-123 - GE Healthcare

Alternative Names: 123I-Iobenguane; 123I-mIBG; 3-iodobenzylguanidine I-123; AdreView; Iobenguane I123 Injection; Metaiodobenzylguanidine I-123 - GE Healthcare

Latest Information Update: 04 Sep 2018

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At a glance

  • Originator GE Healthcare
  • Developer GE Healthcare; University of Ottawa Heart Institute
  • Class Antineoplastics; Guanidines; Iodobenzenes; Radiopharmaceuticals; Small molecules; Sulfates
  • Mechanism of Action Diagnostic imaging enhancers; Enzyme inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Neuroendocrine tumours
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Heart failure; Neuroendocrine tumours
  • Registered Neuroblastoma

Most Recent Events

  • 11 Apr 2018 GE Healthcare terminates a phase III trial for Heart failure (Diagnosis) in USA, Canada, France, Italy, Netherlands, Poland, Hungary, Spain, Czech Republic, Germany and Denmark due to lower rate of recruitment of patients (NCT02656329)
  • 01 Jan 2016 GE Healthcare initiates enrolment in a phase-III trial for Heart failure (Diagnosis) in USA (IV) (NCT02656329)
  • 01 Dec 2013 Phase-III clinical trials for Heart failure (Diagnosis) in Canada (IV) (NCT02043522)
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