SHP 610
Alternative Names: HGT-1410; Recombinant human heparan N-sulfatase - Takeda; rhHNS - Takeda; SHP610Latest Information Update: 02 Oct 2021
At a glance
- Originator Shire Pharmaceuticals Group
- Developer Shire
- Class Enzymes
- Mechanism of Action Heparan sulfate sulfatase replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Mucopolysaccharidosis III
Most Recent Events
- 08 Jan 2019 Shire has been acquired and merged into Takeda
- 30 Aug 2018 Discontinued - Phase-II for Mucopolysaccharidosis III (In children, In infants) in United Kingdom, USA, Netherlands, Argentina, France, Germany, Spain, Italy (Intrathecal)
- 01 Nov 2016 Shire discontinued a phase II extension trial for Mucopolysaccharidosis III (In children and infants) in Spain due to unmet primary endpoints in a previous phase IIb study (NCT02350816)