JSM 6427

Drug Profile

JSM 6427

Alternative Names: JSM-6427

Latest Information Update: 04 Mar 2011

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At a glance

  • Originator Jerini Ophthalmic
  • Class Eye disorder therapies; Small molecules
  • Mechanism of Action Integrin alpha 5 beta 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Age-related macular degeneration; Proliferative vitreoretinopathy

Most Recent Events

  • 04 Mar 2011 Development discontinued for Age-related macular degeneration during 2010
  • 10 Apr 2008 Jerini Ophthalmic signs an exclusive licensing and development agreement with PR Pharmaceuticals to develop sustained-release formulations, including JSM 6427 for the treatment of age-related macular degeneration
  • 07 Dec 2007 Jerini Ophthalmic enters into a research collaboration agreement with University College London Institute of Ophthalmology for the development of JSM 6427 in age-related macular degeneration
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