Beraprost modified release - Astellas Pharma/Kaken Pharmaceuticals/Toray Industries
Alternative Names: Beraprost controlled release; Beraprost MR - Astellas Pharma/Kaken Pharmaceuticals/Toray Industries; Beraprost sustained release; Beraprost-SR; Berasus; Careload LA; TRK-100STP; YM 533Latest Information Update: 05 Nov 2023
At a glance
- Originator Toray
- Developer Astellas Pharma; Kaken Pharmaceutical; Toray
- Class 3-ring heterocyclic compounds; Alkynes; Antiplatelets; Benzofurans; Butyric acids; Cyclopentanes; Prostaglandins; Small molecules; Vasodilators
- Mechanism of Action Epoprostenol receptor agonists; Platelet aggregation inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Marketed Pulmonary arterial hypertension
- Discontinued Renal failure; Spinal stenosis
Most Recent Events
- 01 Aug 2014 Toray and Astellas complete a phase II/III trial in Renal failure in China, Hong Kong, Japan, Malaysia, South Korea, Taiwan and Thailand (NCT01090037)
- 01 Feb 2014 Toray Industries completes a phase I trial in Renal impairment in Japan (NCT01443429)
- 01 May 2008 Toray completes enrolment in its phase II trial for Renal failure in Japan (NCT02480751)