Milciclib maleate - Nerviano Medical Sciences/Tiziana Life Sciences
Alternative Names: PHA 848125C; PHA-125; PHA-848125; PHA-848125AC; TZLS-201Latest Information Update: 28 Jun 2024
At a glance
- Originator Nerviano Medical Sciences
- Developer Nerviano Medical Sciences; Tiziana Life Sciences
- Class 3-ring heterocyclic compounds; Amides; Antineoplastics; Piperazines; Pyrazolones; Quinazolines; Small molecules
- Mechanism of Action CDC2 protein kinase inhibitors; Cyclin-dependent kinase 2 inhibitors; Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 5 inhibitors; Cyclin-dependent kinase-activating kinase inhibitors; TrkA receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Liver cancer; Malignant thymoma
- Phase I/II Glioma
- No development reported Malignant-mesothelioma; Solid tumours
Most Recent Events
- 28 Jun 2024 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease) in Unknown (PO, Capsule)
- 31 Dec 2023 Tiziana Life Sciences has patent protection for milciclib maleate worldwide, prior to December 2023
- 31 Dec 2023 Tiziana Life Sciences has patents pending for milciclib maleate worldwide, prior to December 2023