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SAR 422459

Drug Profile

SAR 422459

Alternative Names: ABCA4 gene therapy; ATP-binding transporter gene therapy; SAR-422459; Stargardt disease gene therapy - Oxford BioMedica/Sanofi; StarGen

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Oxford BioMedica
  • Developer Oxford BioMedica; Sanofi
  • Class Eye disorder therapies; Gene therapies
  • Mechanism of Action ATP-binding cassette transporter replacements; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Eye disorders
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Suspended Stargardt disease

Most Recent Events

  • 01 Mar 2021 Sanofi terminates its license for SAR 422459
  • 09 Jun 2020 Sanofi decides to return rights of SAR 422459 to Oxford Biomedica
  • 13 Nov 2019 SAR 422459 is available for licensing as of 31 Oct 2019. https://www.sanofi.com/
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