Drug Profile

Camptothecin/fleximer conjugate

Alternative Names: MER-1001; XMT-1001

Latest Information Update: 12 Jan 2026

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At a glance

Originator Mersana Therapeutics
Class Antineoplastics; Camptothecins; Drug conjugates; Small molecules
Mechanism of Action DNA topoisomerase I inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

No development reported Solid tumours

Most Recent Events

06 Jan 2026 Mersana Therapeutics has been acquired by Day One Biopharmaceuticals
14 May 2018 Mersana Therapeutics has patent protection in USA and foreign countries across its platforms and programmes
14 May 2018 Mersana Therapeutics has patent protection for its Fleximer polymer-based Dolaflexin platform in USA

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