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Pimasertib - Merck Serono/Sanofi

Drug Profile

Pimasertib - Merck Serono/Sanofi

Alternative Names: AS-703026; EMD-1036239; MSC 1936369; MSC 1936369B; MSC1936369A

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Santhera Pharmaceuticals
  • Developer Merck Serono; Sanofi
  • Class Amides; Aminopyridines; Antineoplastics; Small molecules
  • Mechanism of Action Apoptosis stimulants; MAP kinase kinase 1 inhibitors; MAP kinase kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Colorectal cancer; Haematological malignancies; Malignant melanoma; Ovarian cancer; Pancreatic cancer; Solid tumours

Most Recent Events

  • 30 Aug 2018 Discontinued - Phase-II for Malignant melanoma (First-line therapy, Late-stage disease, Metastatic disease) in Belgium, France, Germany, Israel, Italy, Netherlands, New Zealand, South Africa, Spain, Sweden, Switzerland, United Kingdom, Australia, USA (PO)
  • 24 Jun 2018 Biomarkers information updated
  • 30 Nov 2017 EMD Serono and Sanofi completes a phase II trial in Ovarian cancer (Inoperable/Unresectable, Second-line therapy or greater, Monotherapy, Combination therapy) in USA, Australia, Canada, France, Poland, Italy, Belgium and Spain (PO) (NCT01936363) (EudraCT2013-000902-40)
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