Ensifentrine - Verona Pharma
Alternative Names: Ohtuvayre; RPL 554Latest Information Update: 26 Aug 2024
At a glance
- Originator Vernalis
- Developer Verona Pharma
- Class Anti-inflammatories; Antiallergics; Antiasthmatics; Antibronchitics; Antifibrotics; Imines; Isoquinolines; Small molecules; Urea compounds
- Mechanism of Action Cystic fibrosis transmembrane conductance regulator stimulants; Type 3 cyclic nucleotide phosphodiesterase inhibitors; Type 4 cyclic nucleotide phosphodiesterase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Chronic obstructive pulmonary disease
- Phase II Asthma; Bronchiectasis; Cystic fibrosis
- Phase I Allergic asthma
- Discontinued Allergic rhinitis; COVID 2019 infections
Most Recent Events
- 19 Aug 2024 Verona Pharma plans a phase II trial for Bronchiectasis (Inhalation) in September 2024 (NCT06559150)
- 08 Aug 2024 Launched for Chronic obstructive pulmonary disease in USA (Inhalation)
- 26 Jun 2024 Verona Pharma announces intention to launch ensifentrine for Chronic obstructive pulmonary disease (Inhalation) in USA in third quarter of the 2024