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Methoxyamine hydrochloride - TRACON Pharmaceuticals

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Drug Profile

Methoxyamine hydrochloride - TRACON Pharmaceuticals

Alternative Names: Methoxyamine - TRACON; TRC 102

Latest Information Update: 24 Mar 2025

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At a glance

  • Originator Case Western Reserve University
  • Developer Case Western Reserve University; National Cancer Institute (USA); TRACON Pharmaceuticals
  • Class Antineoplastics; Hydroxylamines; Small molecules
  • Mechanism of Action DNA repair inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma; Glioma
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Glioblastoma; Haematological malignancies; Lymphoma; Mesothelioma; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 12 Nov 2024 Discontinued - Phase-I for Haematological malignancies (Combination therapy, Second-line therapy or greater) in USA (IV) (TRACON Pharmaceuticals website, March 2025)
  • 12 Nov 2024 Discontinued - Phase-I for Lymphoma (Second-line therapy or greater, Combination therapy) in USA (PO) (TRACON Pharmaceuticals website, March 2025)
  • 12 Nov 2024 Discontinued - Phase-I for Non-small cell lung cancer (Combination therapy, Late-stage disease) in USA (PO) (TRACON Pharmaceuticals website, March 2025)

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