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Drug Profile

AVTX 006

Alternative Names: AEVI-006; ASP 7486; AVTX-006; CERC-006; OSI-027

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator OSI Pharmaceuticals
  • Developer Aevi Genomic Medicine; OSI Pharmaceuticals
  • Class 2 ring heterocyclic compounds; Antineoplastics; Carboxylic acids; Imidazoles; Indoles; Pyrazines; Small molecules; Triazines
  • Mechanism of Action MTORC1 protein inhibitors; MTORC2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Lymphangioma
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Lymphangioma; Lymphoma; Renal cancer; Solid tumours

Most Recent Events

  • 07 Mar 2022 Avelo Therapeutics withdraws a phase I trial prior enrolment for Lymphangioma in USA as Avelo Therapeutics decided to pursue strategic alternatives for the programme due to early positive results (PO) (NCT04994002)
  • 02 Mar 2022 Discontinued - Preclinical for Lymphangioma in USA (PO)
  • 26 Aug 2021 Cerecor is now called Avalo Therapeutics

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