Axelopran

Drug Profile

Axelopran

Alternative Names: Oral Peripheral Mu Opioid Receptor Antagonist; TD-1211

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Theravance
  • Developer Theravance Biopharma
  • Class Aza compounds; Benzamides; Cyclohexanes; Heterocyclic bicyclo compounds; Laxatives; Small molecules; Tropanes
  • Mechanism of Action Opioid mu receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Constipation

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Constipation(In the elderly, In volunteers) in USA (PO, Capsule)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Constipation(In volunteers) in USA (IV, Infusion)
  • 14 Aug 2015 Phase-II development is ongoing for opioid-induced constipation in USA
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