Empagliflozin - Boehringer Ingelheim/Eli Lilly

Drug Profile

Empagliflozin - Boehringer Ingelheim/Eli Lilly

Alternative Names: BI-10773; Jardiance

Latest Information Update: 14 Aug 2018

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At a glance

  • Originator Boehringer Ingelheim
  • Developer Boehringer Ingelheim; Eli Lilly; Medical University of Vienna; RWTH Aachen University; University of Oxford; Yale University
  • Class Antihyperglycaemics; Benzhydryl compounds; Cardiovascular therapies; Cyclic ethers; Glucosides; Heart failure therapies; Small molecules
  • Mechanism of Action Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cardiovascular disorders; Type 2 diabetes mellitus
  • Phase III Chronic heart failure; Heart failure; Renal failure; Type 1 diabetes mellitus
  • Phase II Acute heart failure

Most Recent Events

  • 02 Jul 2018 Committee for Medicinal Products for Human Use (CHMP) issues positive opinion to expand Jardiance® label to include positive effects on cardiovascular and renal outcomes in European union
  • 25 Jun 2018 Safety data from the phase III EASE 2 and EASE 3 trial in Type 1 diabetes mellitus released by Boehringer Ingelheim and Eli Lilly
  • 11 Jun 2018 Phase-II clinical trials in Acute heart failure in Germany (PO) (NCT03554200)
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