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AVTX 009

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Drug Profile

AVTX 009

Alternative Names: AVTX-009; FL-101; Fl101; IL-1β antibody - Eli Lilly; LY 2189102

Latest Information Update: 02 Jul 2025

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At a glance

  • Originator Eli Lilly and Company
  • Developer Avalo Therapeutics; Eli Lilly and Company; Flame Biosciences
  • Class
  • Mechanism of Action Immunosuppressants; Interleukin 1 beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Hidradenitis suppurativa
  • Discontinued Cardiovascular disorders; Non-small cell lung cancer; Rheumatoid arthritis; Type 2 diabetes mellitus

Most Recent Events

  • 17 Apr 2013 Discontinued - Phase-I for Cardiovascular disorders in USA (Parenteral)
  • 16 Sep 2011 Final efficacy and adverse events data from a phase II trial in Type-2 diabetes mellitus presented at the 47th Annual meeting of the European Association for the Study of Diabetes (EASD-2011)
  • 11 Apr 2011 Discontinued - Phase-II for Type-2 diabetes mellitus in USA (SC)

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