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Canagliflozin - Johnson & Johnson/Mitsubishi Tanabe Pharma Corporation

Drug Profile

Canagliflozin - Johnson & Johnson/Mitsubishi Tanabe Pharma Corporation

Alternative Names: Canagliflozin-hydrate; Canaglu; Invokana; JNJ-28431754; Sulisent; TA-7284

Latest Information Update: 06 Mar 2024

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At a glance

  • Originator Tanabe Seiyaku
  • Developer Daiichi Sankyo Company; Janssen; Johnson & Johnson; Mitsubishi Tanabe Pharma Corporation; Miyazaki University School of Medicine; Mundipharma Medical Company; Tai Tien Pharmaceuticals
  • Class Antihyperglycaemics; Cardiovascular therapies; Glucosides; Heart failure therapies; Obesity therapies; Small molecules; Thiophenes
  • Mechanism of Action Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Diabetic nephropathies; Type 2 diabetes mellitus
  • Phase III Heart failure
  • Phase II Obesity; Type 1 diabetes mellitus

Most Recent Events

  • 04 Mar 2024 Mitsubishi Tanabe Pharma Corporation and Daiichi Sankyo company plans to terminate its marketing agreement for Canagliflozin in Japan on September 02, 2024
  • 20 Sep 2023 Janssen completes a phase-III trial in Type-2 diabetes mellitus (In children, In adolescents) in USA, Brazil, China, Greece, India, Malaysia, Philippines Mexico, Russia, and Poland (PO) (NCT03170518)
  • 20 Mar 2023 Preregistration for Diabetic nephropathies in Japan (PO)
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