Canagliflozin - Johnson & Johnson/ Mitsubishi Tanabe Pharma Corporation

Drug Profile

Canagliflozin - Johnson & Johnson/ Mitsubishi Tanabe Pharma Corporation

Alternative Names: Canagliflozin-hydrate; Canaglu; Invokana; JNJ-28431754; Sulisent; TA-7284

Latest Information Update: 10 Jul 2018

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At a glance

  • Originator Tanabe Seiyaku
  • Developer Daiichi Sankyo Company; Janssen; Johnson & Johnson; Mitsubishi Tanabe Pharma Corporation; Miyazaki University School of Medicine
  • Class Antihyperglycaemics; Glucosides; Small molecules; Thiophenes
  • Mechanism of Action Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Type 2 diabetes mellitus
  • Phase III Diabetic nephropathies
  • Phase II Heart failure; Obesity; Type 1 diabetes mellitus

Most Recent Events

  • 26 Jun 2018 Launched for Type-2 diabetes mellitus in China (PO) prior to June, 2018 (CFDA registry, June 2018)
  • 22 Jun 2018 Long-term safety data from CANVAS program in Type-2 diabetes mellitus presented at the 78th Annual Scientific Sessions of the American Diabetes Association (ADA-2018)
  • 13 Apr 2018 Efficacy and safety data from CANVAS program in Type-2 diabetes mellitus and Chronic kidney disease released by Janssen Pharmaceutical
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