MSB 0010445

Drug Profile

MSB 0010445

Alternative Names: EMD 521873; MSB0010445; NHS-IL2; NHS-IL2-LT; Selectikine

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator EMD Serono; Merck Serono
  • Class Antineoplastics; Cytokines; Immunoconjugates; Recombinant fusion proteins
  • Mechanism of Action Interleukin-2 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Malignant melanoma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 30 Nov 2013 Phase-II clinical trials in Malignant melanoma (second-line therapy or greater, late-stage disease) in USA (IV)
  • 25 Oct 2013 EMD Serono plans a phase IIa trial for Malignant melanoma (unresectable or metastatic disease) in USA (NCT01973608)
  • 31 Jan 2012 Merck completes a phase I trial in Non-Hodgkin's lymphoma and Solid tumours in Germany and Switzerland (NCT00879866)
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