Caplacizumab - Ablynx
Alternative Names: ALX-0081; ALX-0681; Anti-von Willebrand factor Nanobody® - Ablynx; Cablivi; caplacizumab-yhdpLatest Information Update: 18 Dec 2025
At a glance
- Originator Ablynx
- Developer Ablynx; Sanofi
- Class Anticoagulants; Antithrombotics; Monoclonal antibodies; Proteins; Recombinant proteins; Single-domain antibodies
- Mechanism of Action Platelet aggregation inhibitors; Von Willebrand factor inhibitors
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Orphan Drug Status
Yes - Thrombotic thrombocytopenic purpura
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Marketed Thrombotic thrombocytopenic purpura
- Discontinued Thrombosis
Most Recent Events
- 11 Dec 2025 Preregistration for Thrombotic thrombocytopenic purpura (In children, In adolescents, In adults) in China (IV), prior to December 2025
- 11 Dec 2025 Preregistration for Thrombotic thrombocytopenic purpura (In children, In adolescents, In adults) in China (SC), prior to December 2025
- 11 Dec 2025 Registered for Thrombotic thrombocytopenic purpura (In children, In adolescents, In adults) in China (IV)