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Caplacizumab - Ablynx

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Drug Profile

Caplacizumab - Ablynx

Alternative Names: ALX-0081; ALX-0681; Anti-von Willebrand factor Nanobody® - Ablynx; Cablivi; caplacizumab-yhdp

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Ablynx
  • Developer Ablynx; Sanofi
  • Class Anticoagulants; Antithrombotics; Monoclonal antibodies; Proteins; Recombinant proteins; Single-domain antibodies
  • Mechanism of Action Platelet aggregation inhibitors; Von Willebrand factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Thrombotic thrombocytopenic purpura
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Thrombotic thrombocytopenic purpura
  • Discontinued Thrombosis

Most Recent Events

  • 28 Oct 2022 Registered for Thrombotic thrombocytopenic purpura in Japan (SC) prior to October 2022
  • 28 Oct 2022 Registered for Thrombotic thrombocytopenic purpura in Japan prior to October 2022 (IV)
  • 06 Sep 2022 No development reported - Phase-II/III for Thrombotic thrombocytopenic purpura (Adjunctive treatment) in Japan (IV) (NDR Batch 23)

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