Research programme: TT 223 + CD26 antigen antagonists - Transition Therapeutics

Drug Profile

Research programme: TT 223 + CD26 antigen antagonists - Transition Therapeutics

Alternative Names: G1 + CD26 antigen antagonists; TT 223 + CD26 antigen antagonists; TT-223 + DPP-IV inhibitors

Latest Information Update: 20 May 2008

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At a glance

  • Originator Transition Therapeutics
  • Class Antihyperglycaemics; Carrier proteins; CD antigens; Gastrointestinal hormones; Hormones; Neuropeptides; Peptide hormones
  • Mechanism of Action CD26 antigen inhibitors; Gastrin stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Diabetes mellitus

Most Recent Events

  • 20 May 2008 Discontinued - Preclinical for Diabetes mellitus in Canada (Injection/PO combination)
  • 14 Mar 2008 Transition Therapeutics and Eli Lilly enter into a licensing and collaboration agreement for gastrin-based therapies in Diabetes
  • 06 Jul 2007 Preclinical trials in Diabetes mellitus in Canada (unspecified route)
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