MK 5108

Drug Profile

MK 5108

Alternative Names: MK-5108; VX-689

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Vertex Pharmaceuticals
  • Developer Merck & Co
  • Class Antineoplastics
  • Mechanism of Action Aurora kinase A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in USA (PO)
  • 23 Mar 2011 Phase-I development is ongoing in USA (NCT00543387)
  • 08 Jun 2010 Adverse events, efficacy and pharmacokinetics data from a phase I trial in late-stage and/or refractory solid tumours presented at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO-2010)
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