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Dipraglurant - Addex Therapeutics

Drug Profile

Dipraglurant - Addex Therapeutics

Alternative Names: ADX-48621; Dipraglurant-ER; Dipraglurant-IR; mGluR5-NAM

Latest Information Update: 17 Aug 2023

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At a glance

  • Originator Addex Pharmaceuticals
  • Developer Addex Therapeutics
  • Class Alkynes; Antidepressants; Anxiolytics; Heterocyclic bicyclo compounds; Imidazoles; Muscle relaxants; Neuropsychotherapeutics; Pyridines; Small molecules
  • Mechanism of Action Metabotropic glutamate receptor 5 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Drug-induced dyskinesia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Drug-induced dyskinesia
  • Phase II Blepharospasm; Torticollis
  • Preclinical Neurological disorders
  • No development reported Major depressive disorder
  • Discontinued Anxiety disorders

Most Recent Events

  • 10 Aug 2023 Preclinical trials in Neurological disorders in Switzerland (unspecified route)
  • 10 Aug 2023 Addex Therapeutics plans a phase II trial for Neurological disorders in 2024.
  • 04 Apr 2023 Pharmacodynamics data from preclinical study in Parkinson's disease released by Addex Therapeutics
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