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Evenamide - Newron Pharmaceuticals

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Drug Profile

Evenamide - Newron Pharmaceuticals

Alternative Names: NW-3509; NW-3509A

Latest Information Update: 13 Jun 2025

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At a glance

  • Originator Newron Pharmaceuticals
  • Class Antidepressants; Antiepileptic drugs; Antimanics; Antipsychotics; Non-opioid analgesics; Small molecules
  • Mechanism of Action Dopamine D2 receptor agonists; Dopamine D2 receptor antagonists; Nav1.3 voltage-gated sodium channel inhibitors; NAV1.7 voltage gated sodium channel expression inhibitors; Nav1.7 voltage-gated sodium channel inhibitors; NAV1.8 voltage gated sodium channel expression inhibitors; Nav1.8 voltage-gated sodium channel inhibitors; Serotonin 5-HT2 receptor agonists; Serotonin 5-HT2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Schizophrenia
  • Phase II/III Psychiatric disorders

Most Recent Events

  • 12 Jun 2025 Newron Pharmaceuticals plans a phase III ENIGMA-TRS 1 trial for Schizophrenia (Treatment-resistant) in Europe, Asia, Latin America and Canada
  • 12 May 2025 US FDA approves ENIGMA-TRS 2 phase III clinical trial for Evenamide in Schizophrenia (Treatment resistant)
  • 09 Jan 2025 Newron Pharmaceuticals and Myung In Pharm entered into licensing agreement for Evenamide

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