Drug Profile

552 02

Alternative Names: 552; CF-552; KM-003; KM-552; KM003/P552; P-552; P-552-02

Latest Information Update: 09 Feb 2016

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At a glance

Originator Parion Sciences
Developer Kainos Medicines; Parion Sciences
Class Guanidines; Pyrazines; Small molecules
Mechanism of Action Epithelial sodium channel antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Bronchiectasis; Bronchitis; Chronic obstructive pulmonary disease; Cystic fibrosis; Radiation injuries; Xerostomia

Most Recent Events

25 Nov 2014 Discontinued - Preclinical for Bronchiectasis in USA (unspecified route)
25 Nov 2014 Discontinued - Preclinical for Bronchitis in USA (unspecified route)
25 Nov 2014 Discontinued - Preclinical for Radiation injuries in USA (unspecified route)

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